Description
Product Characteristics:
Aliases: MIG9 antibody, Migration inducing gene 9 antibody, Protein S100-E antibody, Protein S100-P antibody, Protein S100P antibody, S100 calcium binding protein P antibody, S100 calcium-binding protein P antibody, S100 P antibody, S100E antibody, S100P antibody, S100P_HUMAN antibody
Target Information: The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq, Jul 2008]